| Spell Pierce (6 variants) | 51 |
| Soul Warden (6 variants) | 24 |
| Soul Ransom (6 variants) | 186 |
| Soul Manipulation (6 variants) | 185 |
| Snapcaster Mage (6 variants) | 50 |
| Slime Molding (6 variants) | 137 |
| Slaughterhorn (6 variants) | 136 |
| Skyknight Legionnaire (6 variants) | 184 |
| Skirsdag Cultist (6 variants) | 112 |
| Sin Collector (6 variants) | 183 |
| Simic Sky Swallower (6 variants) | 182 |
| Simic Signet (6 variants) | 227 |
| Simic Guildgate (6 variants) | 248 |
| Shimmering Grotto (6 variants) | 247 |
| Sever the Bloodline (6 variants) | 84 |
| Serum Visions (6 variants) | 49 |
| Sensor Splicer (6 variants) | 23 |
| Selesnya Signet (6 variants) | 226 |
| Selesnya Guildgate (6 variants) | 246 |
| Sedraxis Specter (6 variants) | 181 |
| Seaside Citadel (6 variants) | 245 |
| Séance (6 variants) | 22 |
| Seal of Primordium (6 variants) | 135 |
| Seal of Doom (6 variants) | 83 |
| Sea Gate Oracle (6 variants) | 48 |
| Scourge Devil (6 variants) | 111 |
| Scorched Rusalka (6 variants) | 110 |
| Scavenging Ooze (6 variants) | 134 |
| Scalding Tarn (6 variants) | 244 |
| Savage Lands (6 variants) | 243 |
| Rubblebelt Maaka (6 variants) | 109 |
| Rootborn Defenses (6 variants) | 21 |
| Rhox War Monk (6 variants) | 180 |
| Rewind (6 variants) | 47 |
| Revive (6 variants) | 133 |
| Restoration Angel (6 variants) | 20 |
| Recover (6 variants) | 82 |
| Ranger of Eos (6 variants) | 19 |
| Rakdos Signet (6 variants) | 225 |
| Rakdos Guildgate (6 variants) | 242 |
| Pyromancer Ascension (6 variants) | 108 |
| Pyroclasm (6 variants) | 107 |
| Pyrewild Shaman (6 variants) | 106 |
| Putrefy (6 variants) | 179 |
| Primal Command (6 variants) | 132 |
| Pitfall Trap (6 variants) | 18 |
| Pit Keeper (6 variants) | 81 |
| Pilfered Plans (6 variants) | 178 |
| Phantasmal Image (6 variants) | 46 |
| Penumbra Spider (6 variants) | 131 |