| Static Prison (16 variants) | 44 |
| Spymaster's Vault (16 variants) | 358 |
| Spymaster's Vault (16 variants) | 230 |
| Springheart Nantuko (16 variants) | 171 |
| Springheart Nantuko (16 variants) | 341 |
| Spawn-Gang Commander (16 variants) | 140 |
| Sowing Mycospawn (16 variants) | 170 |
| Sowing Mycospawn (16 variants) | 340 |
| Sorin of House Markov // Sorin, Ravenous Neonate | 470 |
| Sorin of House Markov // Sorin, Ravenous Neonate (16 variants) | 444 |
| Sorin of House Markov // Sorin, Ravenous Neonate (4 variants) | 245 |
| Solstice Zealot (16 variants) | 43 |
| Solar Transformer (16 variants) | 211 |
| Solar Transformer | 519 |
| Snow-Covered Wastes (16 variants) | 439 |
| Snow-Covered Wastes (16 variants) | 309 |
| Snow-Covered Wastes (16 variants) | 229 |
| Sneaky Snacker (16 variants) | 205 |
| Snapping Voidcraw (16 variants) | 204 |
| Snapping Voidcraw | 517 |
| Smelted Chargebug (16 variants) | 139 |
| Skoa, Embermage (16 variants) | 138 |
| Skoa, Embermage (16 variants) | 420 |
| Skittering Precursor (16 variants) | 137 |
| Six (5 variants) | 484 |
| Six (16 variants) | 370 |
| Six (16 variants) | 169 |
| Six (16 variants) | 430 |
| Sink into Stupor // Soporific Springs (16 variants) | 241 |
| Signature Slam (16 variants) | 168 |
| Siege Smash (16 variants) | 136 |
| Shrieking Drake (16 variants) | 272 |
| Shilgengar, Sire of Famine (16 variants) | 109 |
| Shilgengar, Sire of Famine (5 variants) | 480 |
| Shilgengar, Sire of Famine (16 variants) | 366 |
| Shifting Woodland (16 variants) | 357 |
| Shifting Woodland (16 variants) | 228 |
| Sheltering Landscape (16 variants) | 227 |
| Shattered Landscape (16 variants) | 226 |
| Shadow of the Second Sun (16 variants) | 70 |
| Shadow of the Second Sun (16 variants) | 402 |
| Sevinne's Reclamation (16 variants) | 267 |
| Serum Visionary (16 variants) | 69 |
| Seething Landscape (16 variants) | 225 |
| Scurry of Gremlins (16 variants) | 203 |
| Scurry of Gremlins | 516 |
| Scurrilous Sentry (16 variants) | 108 |
| Sarpadian Simulacrum (16 variants) | 135 |
| Sapphire Medallion (16 variants) | 296 |
| Sapphire Medallion (16 variants) | 349 |