| Sphinx's Revelation (22 variants) | 200 |
| Sphinx of the Chimes (22 variants) | 52 |
| Sphere of Safety (22 variants) | 24 |
| Spawn of Rix Maadi (22 variants) | 199 |
| Soulsworn Spirit (22 variants) | 51 |
| Soul Tithe (22 variants) | 23 |
| Slum Reaper (22 variants) | 77 |
| Sluiceway Scorpion (22 variants) | 198 |
| Slitherhead (22 variants) | 222 |
| Slime Molding (22 variants) | 135 |
| Slaughter Games (22 variants) | 197 |
| Skymark Roc (22 variants) | 196 |
| Skyline Predator (22 variants) | 50 |
| Skull Rend (22 variants) | 195 |
| Shrieking Affliction (22 variants) | 76 |
| Sewer Shambler (22 variants) | 75 |
| Seller of Songbirds (22 variants) | 22 |
| Selesnya Sentry (22 variants) | 21 |
| Selesnya Keyrune (22 variants) | 233 |
| Selesnya Guildgate (22 variants) | 246 |
| Selesnya Charm (22 variants) | 194 |
| Seek the Horizon (22 variants) | 134 |
| Security Blockade (22 variants) | 20 |
| Search Warrant (22 variants) | 193 |
| Search the City (22 variants) | 49 |
| Savage Surge (22 variants) | 133 |
| Runewing (22 variants) | 48 |
| Rubbleback Rhino (22 variants) | 132 |
| Rootborn Defenses (22 variants) | 19 |
| Rogue's Passage (22 variants) | 245 |
| Rix Maadi Guildmage (22 variants) | 192 |
| Rites of Reaping (22 variants) | 191 |
| Risen Sanctuary (22 variants) | 190 |
| Righteous Authority (22 variants) | 189 |
| Rest in Peace (22 variants) | 18 |
| Rakdos's Return (22 variants) | 188 |
| Rakdos, Lord of Riots (22 variants) | 187 |
| Rakdos Shred-Freak (22 variants) | 221 |
| Rakdos Ringleader (22 variants) | 186 |
| Rakdos Ragemutt (22 variants) | 185 |
| Rakdos Keyrune (22 variants) | 232 |
| Rakdos Guildgate (22 variants) | 244 |
| Rakdos Charm (22 variants) | 184 |
| Rakdos Cackler (22 variants) | 220 |
| Racecourse Fury (22 variants) | 104 |
| Pyroconvergence (22 variants) | 103 |
| Pursuit of Flight (22 variants) | 102 |
| Psychic Spiral (22 variants) | 47 |
| Precinct Captain (22 variants) | 17 |
| Plains (22 variants) | 250 |