| Sage's Reverie (6 variants) | 165 |
| Sakura-Tribe Elder | 285 |
| Scorched Geyser (4 variants) | 102 |
| Scorched Geyser (6 variants) | 54 |
| Screams from Within (6 variants) | 119 |
| Scriv, the Obligator (8 variants) | 9 |
| Secret Rendezvous (6 variants) | 166 |
| Selfless Spirit (6 variants) | 167 |
| Sentinel's Eyes (6 variants) | 168 |
| Serra Paragon (6 variants) | 169 |
| Sevinne's Reclamation (6 variants) | 170 |
| Shadrix Silverquill | 330 |
| Sheltered by Ghosts (6 variants) | 171 |
| Shielded by Faith (6 variants) | 172 |
| Shineshadow Snarl | 403 |
| Shivan Reef | 404 |
| Silkguard | 286 |
| Silverquill Campus | 405 |
| Skyclave Apparition (6 variants) | 173 |
| Smothering Abomination (6 variants) | 226 |
| Sodden Verdure | 406 |
| Sol Ring (6 variants) | 128 |
| Sol Ring | 427 |
| Solemn Simulacrum | 355 |
| Songbirds' Blessing (6 variants) | 174 |
| Spirit Mantle (6 variants) | 175 |
| Spirit of Resilience (6 variants) | 37 |
| Spirit of Resilience (4 variants) | 85 |
| Springbloom Druid | 287 |
| Squee, Goblin Nabob (6 variants) | 254 |
| Sram, Senior Edificer (6 variants) | 176 |
| Staff of the Storyteller (6 variants) | 111 |
| Starfield Mystic (6 variants) | 177 |
| Steelbane Hydra | 288 |
| Stensian Sanguinist // Exsanguinate (6 variants) | 29 |
| Stensian Sanguinist // Exsanguinate (4 variants) | 78 |
| Stonecoil Serpent | 356 |
| Storm-Kiln Artist (6 variants) | 255 |
| Stormcatch Mentor | 331 |
| Striding Shotcaller // Run the Play (6 variants) | 50 |
| Striding Shotcaller // Run the Play (4 variants) | 98 |
| Stroke of Genius (6 variants) | 203 |
| Study Hall | 407 |
| Sulfur Falls | 408 |
| Sun Titan (6 variants) | 178 |
| Sunlit Marsh | 409 |
| Sunscorched Divide | 410 |
| Surge to Victory (6 variants) | 256 |
| Swords to Plowshares (6 variants) | 179 |
| Talisman of Conviction | 428 |