| Scourge of Nel Toth (7 variants) | 21 |
| Scytheclaw (7 variants) | 53 |
| Seal of Cleansing (7 variants) | 79 |
| Seal of Doom (7 variants) | 135 |
| Seal of the Guildpact (7 variants) | 54 |
| Secluded Steppe (7 variants) | 304 |
| Seer's Sundial (7 variants) | 264 |
| Sever the Bloodline (7 variants) | 136 |
| Shielded by Faith (7 variants) | 8 |
| Shriekmaw (7 variants) | 137 |
| Sigil of the Empty Throne (7 variants) | 80 |
| Silent Sentinel (7 variants) | 81 |
| Simic Growth Chamber (7 variants) | 305 |
| Simic Guildgate (7 variants) | 306 |
| Simic Keyrune (7 variants) | 265 |
| Simic Signet (7 variants) | 266 |
| Skullclamp (7 variants) | 267 |
| Skullwinder (7 variants) | 39 |
| Sleep (7 variants) | 106 |
| Slippery Karst (7 variants) | 307 |
| Smoldering Crater (7 variants) | 308 |
| Snakeform (7 variants) | 242 |
| Sol Ring (7 variants) | 268 |
| Solemn Simulacrum (7 variants) | 269 |
| Spider Spawning (7 variants) | 202 |
| Spinerock Knoll (7 variants) | 309 |
| Staff of Nin (7 variants) | 270 |
| Steam Augury (7 variants) | 233 |
| Stingerfling Spider (7 variants) | 203 |
| Stinkdrinker Daredevil (7 variants) | 164 |
| Stolen Goods (7 variants) | 107 |
| Stoneshock Giant (7 variants) | 165 |
| Stroke of Genius (7 variants) | 108 |
| Sun Titan (7 variants) | 82 |
| Sunrise Sovereign (7 variants) | 166 |
| Swamp (7 variants) | 332 |
| Swamp (7 variants) | 331 |
| Swamp (7 variants) | 334 |
| Swamp (7 variants) | 333 |
| Swiftfoot Boots (7 variants) | 271 |
| Swiftwater Cliffs (7 variants) | 310 |
| Sword of Vengeance (7 variants) | 272 |
| Synthetic Destiny (7 variants) | 15 |
| Tainted Field (7 variants) | 311 |
| Tainted Wood (7 variants) | 312 |
| Talrand, Sky Summoner (7 variants) | 109 |
| Taurean Mauler (7 variants) | 167 |
| Temple of the False God (7 variants) | 313 |
| Terastodon (7 variants) | 204 |
| Terramorphic Expanse (7 variants) | 314 |