| Spore Crawler (2 variants) | 218 |
| Spontaneous Mutation (2 variants) | 86 |
| Splinterfright (2 variants) | 420 |
| Splinterfright (2 variants) | 217 |
| Spider Spawning (2 variants) | 216 |
| Spider Spawning (2 variants) | 419 |
| Spell Queller (2 variants) | 320 |
| Spell Queller (2 variants) | 248 |
| Spell Queller (2 variants) | 435 |
| Spectral Shepherd (2 variants) | 349 |
| Spectral Shepherd (2 variants) | 41 |
| Soulcipher Board // Cipherbound Spirit (2 variants) | 459 |
| Soulcipher Board // Cipherbound Spirit (2 variants) | 85 |
| Soul-Guide Gryff (2 variants) | 40 |
| Soul Separator (2 variants) | 446 |
| Soul Separator (2 variants) | 270 |
| Sorin, Imperious Bloodlord (2 variants) | 322 |
| Sorin, Imperious Bloodlord (2 variants) | 133 |
| Sorin, Imperious Bloodlord (2 variants) | 476 |
| Somberwald Sage (2 variants) | 418 |
| Somberwald Sage (2 variants) | 215 |
| Snapcaster Mage (2 variants) | 478 |
| Smoldering Werewolf // Erupting Dreadwolf (2 variants) | 465 |
| Smoldering Werewolf // Erupting Dreadwolf (2 variants) | 171 |
| Slayer of the Wicked (2 variants) | 348 |
| Slayer of the Wicked (2 variants) | 39 |
| Skirsdag High Priest (2 variants) | 132 |
| Silent Departure (2 variants) | 367 |
| Silent Departure (2 variants) | 84 |
| Sigarda, Host of Herons (2 variants) | 434 |
| Sigarda, Host of Herons (2 variants) | 247 |
| Siege Zombie (2 variants) | 131 |
| Shrill Howler // Howling Chorus (2 variants) | 214 |
| Shrill Howler // Howling Chorus (2 variants) | 469 |
| Shipwreck Marsh (2 variants) | 284 |
| Shattered Sanctum (2 variants) | 283 |
| Sever the Bloodline (2 variants) | 389 |
| Sever the Bloodline (2 variants) | 130 |
| Seize the Storm (2 variants) | 170 |
| Seize the Storm (2 variants) | 401 |
| Second Harvest (2 variants) | 213 |
| Second Harvest (2 variants) | 417 |
| Scorned Villager // Moonscarred Werewolf (2 variants) | 212 |
| Scorned Villager // Moonscarred Werewolf (2 variants) | 468 |
| Savage Alliance (2 variants) | 169 |
| Sanitarium Skeleton (2 variants) | 129 |
| Runebound Wolf (2 variants) | 168 |
| Rooftop Storm (2 variants) | 83 |
| Rooftop Storm (2 variants) | 306 |
| Rockfall Vale (2 variants) | 282 |