| Snapcaster Mage (4 variants) | 808 |
| Snap (4 variants) | 2247 |
| Snap (2 variants) | 412 |
| Smuggler's Copter // Smuggler's Copter (2 variants) | 1968 |
| Smuggler's Copter (2 variants) | 446 |
| Smothering Tithe | 7009 |
| Sliver Overlord | 10 |
| Sliver Legion | 1310 |
| Sliver Legion (2 variants) | 1149 |
| Sliver Legion (2 variants) | 1150 |
| Sliver Hivelord (2 variants) | 276 |
| Sliver Hive | 668 |
| Slip On the Ring (2 variants) | 1293 |
| Slimefoot, the Stowaway (2 variants) | 1138 |
| Slime Against Humanity (2 variants) | 7078 |
| Slime Against Humanity (2 variants) | 7077 |
| Slime Against Humanity | 7083 |
| Slayers' Stronghold (2 variants) | 356 |
| Skysovereign, Consul Flagship (2 variants) | 1029 |
| Skyshroud Claim (2 variants) | 2279 |
| Skyline Despot | 1529 |
| Skullclamp (2 variants) | 1663 |
| Skullclamp | 2416 |
| Skullclamp (4 variants) | 1112 |
| Skrelv, Defector Mite (2 variants) | 1926 |
| Skithiryx, the Blight Dragon (2 variants) | 1562 |
| Skirk Prospector | 2414 |
| Skewer the Critics (2 variants) | 2051 |
| Skewer the Critics | 2056 |
| Skemfar Shadowsage | 759 |
| Six | 2660 |
| Sisay, Weatherlight Captain (2 variants) | 9999 |
| Sisay, Weatherlight Captain (2 variants) | 1444 |
| Sire of Insanity (2 variants) | 275 |
| Simon, Wild Magic Sorcerer (2 variants) | 1238 |
| Simic Signet (2 variants) | 295 |
| Simic Ascendancy | 1832 |
| Simian Spirit Guide | 1548★ |
| Simian Spirit Guide | 1548 |
| Silver Shroud Costume | 915 |
| Silence (2 variants) | 1445 |
| Silence (2 variants) | 7003 |
| Silence (2 variants) | 2300 |
| Silence | 881 |
| Silence (2 variants) | 1816 |
| Sigarda's Aid (2 variants) | 1727 |
| Sigarda's Aid | 731 |
| Sidewinder Sliver | 615 |
| Shrine | 1835 |
| Shorikai, Genesis Engine (2 variants) | 1880 |