| Empress Galina (2 variants) | 9998 |
| Empty the Warrens | 2412 |
| Emrakul, the Promised End (2 variants) | 1160 |
| Enchanted Evening (2 variants) | 122 |
| End the Festivities (2 variants) | 2503 |
| Endurance | 7008 |
| Enduring Ideal | 887 |
| Ephara, God of the Polis | 72 |
| Ephemerate (2 variants) | 1990 |
| Erebos, God of the Dead | 74 |
| Ertai, the Corrupted | 1216 |
| Escape to the Wilds (2 variants) | 1921 |
| Escape to the Wilds (2 variants) | 1916 |
| Esika, God of the Tree // The Prismatic Bridge | 1208 |
| Esika, God of the Tree // The Prismatic Bridge | 1155 |
| Esika's Chariot (2 variants) | 1894 |
| Essence Sliver | 612 |
| Estrid, the Masked // Estrid, the Masked | 1327 |
| Estrid's Invocation // Estrid's Invocation | 1325 |
| Etali, Primal Storm | 1389★ |
| Etali, Primal Storm | 1389 |
| Etali, Primal Storm // Etali, Primal Storm (2 variants) | 1123 |
| Eternal Witness | 1522★ |
| Eternal Witness | 43 |
| Eternal Witness | 1522 |
| Etherium Sculptor (2 variants) | 443 |
| Ethersworn Canonist (2 variants) | 2102 |
| Evolution Sage | 765 |
| Evolving Wilds (2 variants) | 538 |
| Evolving Wilds | 824 |
| Exotic Orchard (2 variants) | 1231 |
| Expedition Map (2 variants) | 7053 |
| Explore | 2327 |
| Explore (2 variants) | 2312 |
| Explore (2 variants) | 114 |
| Expressive Iteration (4 variants) | 2060 |
| Expressive Iteration (2 variants) | 2305 |
| Expropriate | 2396 |
| Exquisite Blood (2 variants) | 1798 |
| Exquisite Blood (2 variants) | 206 |
| Fabled Passage | 727 |
| Fabled Passage | 1534 |
| Fabled Passage | 1534★ |
| Fabled Passage | 471 |
| Fabricate | 7124 |
| Fabricate (2 variants) | 332 |
| Fabricate (2 variants) | 2090 |
| Fabricate (2 variants) | 7118 |
| Fabricate (2 variants) | 1084 |
| Fabricate (2 variants) | 7121 |