| Scholar of New Horizons | 7143 |
| Scheming Symmetry | 1520★ |
| Scheming Symmetry | 1520 |
| Scheming Symmetry (2 variants) | 1997 |
| Scavenging Ooze | 135 |
| Scattered Groves (2 variants) | 2523 |
| Scaled Nurturer (2 variants) | 7101 |
| Saw in Half (2 variants) | 1755 |
| Savra, Queen of the Golgari (2 variants) | 500 |
| Savor the Moment (2 variants) | 1006 |
| Satoru Umezawa (2 variants) | 2283 |
| Saskia the Unyielding | 55 |
| Sarulf, Realm Eater (4 variants) | 2240 |
| Sarkhan, Dragonsoul | 1245 |
| Sarkhan Vol (2 variants) | 1144 |
| Sarkhan the Masterless | 514 |
| Saproling (2 variants) | 1139 |
| Sanguine Bond (2 variants) | 1799 |
| Sanctum Prelate (2 variants) | 278 |
| Samut, Voice of Dissent (2 variants) | 1451 |
| Samut, Tyrant Smasher | 535 |
| Sakura-Tribe Elder (2 variants) | 192 |
| Sakura-Tribe Elder (2 variants) | 2518 |
| Sakashima's Student (2 variants) | 2359 |
| Sakashima's Student (2 variants) | 2355 |
| Sakashima the Impostor (2 variants) | 1232 |
| Sakashima of a Thousand Faces // Sakashima of a Thousand Faces (2 variants) | 1541 |
| Saheeli, Sublime Artificer | 534 |
| Saheeli, Sublime Artificer (2 variants) | 1143 |
| Sacred Foundry | 131 |
| Ryu, World Warrior (2 variants) | 429 |
| Rune-Scarred Demon (2 variants) | 2649 |
| Rule of Law (2 variants) | 2478 |
| Ruinous Ultimatum (2 variants) | 2689 |
| Ruination (2 variants) | 9993 |
| Ruin Crab (2 variants) | 7095 |
| Ruhan of the Fomori (2 variants) | 1695 |
| Rotting Regisaur | 852 |
| Rot Hulk | 851 |
| Rose Noble (2 variants) | 1580 |
| Rootbound Crag (2 variants) | 459 |
| Root Sliver | 656 |
| Roon of the Hidden Realm (2 variants) | 2173 |
| Roiling Vortex (2 variants) | 1958 |
| Roil Elemental (2 variants) | 155 |
| Rogue's Passage | 607 |
| Rogue's Passage (2 variants) | 2652 |
| Rograkh, Son of Rohgahh (2 variants) | 9996 |
| Roaming Throne | 2415 |
| Rites of Flourishing (2 variants) | 2074 |