| Evolution Sage | 765 |
| Ethersworn Canonist (2 variants) | 2102 |
| Etherium Sculptor (2 variants) | 443 |
| Eternal Witness | 1522★ |
| Eternal Witness | 43 |
| Eternal Witness | 1522 |
| Etali, Primal Storm // Etali, Primal Storm (2 variants) | 1123 |
| Etali, Primal Storm | 1389★ |
| Etali, Primal Storm | 1389 |
| Estrid's Invocation // Estrid's Invocation | 1325 |
| Estrid, the Masked // Estrid, the Masked | 1327 |
| Essence Sliver | 612 |
| Esika's Chariot (2 variants) | 1894 |
| Esika, God of the Tree // The Prismatic Bridge | 1208 |
| Esika, God of the Tree // The Prismatic Bridge | 1155 |
| Escape to the Wilds (2 variants) | 1921 |
| Escape to the Wilds (2 variants) | 1916 |
| Ertai, the Corrupted | 1216 |
| Erebos, God of the Dead | 74 |
| Ephemerate (2 variants) | 1990 |
| Ephara, God of the Polis | 72 |
| Enduring Ideal | 887 |
| Endurance | 7008 |
| End the Festivities (2 variants) | 2503 |
| Enchanted Evening (2 variants) | 122 |
| Emrakul, the Promised End (2 variants) | 1160 |
| Empty the Warrens | 2412 |
| Empress Galina (2 variants) | 9998 |
| Emeria, the Sky Ruin (2 variants) | 1291 |
| Elvish Visionary | 763 |
| Elvish Vanguard | 762 |
| Elvish Spirit Guide (2 variants) | 423 |
| Elvish Reclaimer (2 variants) | 2015 |
| Elvish Mystic (2 variants) | 475 |
| Elvish Mystic (4 variants) | 805 |
| Elvish Champion | 761 |
| Elves of Deep Shadow (2 variants) | 1710 |
| Elspeth, Sun's Champion (2 variants) | 1140 |
| Elspeth, Knight-Errant (2 variants) | 1001 |
| Elspeth, Knight-Errant (2 variants) | 701 |
| Elspeth Tirel (4 variants) | 1585 |
| Ellie, Vengeful Hunter (2 variants) | 2203 |
| Ellie, Brick Master (2 variants) | 2197 |
| Elixir of Immortality | 1634★ |
| Elixir of Immortality | 1634 |
| Elf Warrior | 7170 |
| Elf Warrior | 7169 |
| Elf Warrior | 7168 |
| Eleven, the Mage (2 variants) | 343 |
| Elesh Norn, Grand Cenobite | 811 |